Ari Ristimäki Selected Research

Transforming Growth Factor beta (TGF-beta)

1/2021	Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling.
11/2008	Smad4 haploinsufficiency: a matter of dosage.
4/2008	LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
8/2003	Ski-related novel protein N (SnoN), a negative controller of transforming growth factor-beta signaling, is a prognostic marker in estrogen receptor-positive breast carcinomas.

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Ari Ristimäki Research Topics

Disease

83	Neoplasms (Cancer) 05/2024 - 02/2002
29	Carcinogenesis 01/2021 - 02/2002
19	Adenocarcinoma 05/2024 - 02/2002
18	Stomach Neoplasms (Stomach Cancer) 05/2024 - 02/2002
16	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 03/2008
12	Carcinoma (Carcinomatosis) 11/2023 - 06/2002
12	Breast Neoplasms (Breast Cancer) 09/2017 - 02/2002
11	Neoplasm Metastasis (Metastasis) 02/2024 - 02/2002
11	Inflammation (Inflammations) 01/2022 - 01/2004
7	Microsatellite Instability 07/2023 - 04/2008
7	Adenoma (Adenomas) 01/2021 - 06/2003
5	Pseudomyxoma Peritonei 01/2021 - 08/2014
4	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 05/2021 - 01/2015
4	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2016
3	Anastomotic Leak 05/2024 - 01/2023
3	Esophageal Neoplasms (Esophageal Cancer) 01/2023 - 12/2022
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2023 - 10/2005
3	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 11/2003
3	Polyps 01/2009 - 04/2008
2	Disease Progression 01/2022 - 01/2017
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 10/2021
2	Residual Neoplasm 01/2022 - 10/2021
2	Genetic Predisposition to Disease (Genetic Predisposition) 11/2021 - 09/2009
2	Ulcerative Colitis 10/2021 - 10/2016
2	Pouchitis 10/2021 - 01/2021
2	Rectal Neoplasms (Rectal Cancer) 01/2020 - 01/2020
2	Ameloblastoma 05/2019 - 04/2014
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2017 - 01/2015
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2017 - 01/2016
2	Melanoma (Melanoma, Malignant) 04/2016 - 02/2015
2	Kidney Neoplasms (Kidney Cancer) 01/2016 - 01/2010
2	Sarcoma (Soft Tissue Sarcoma) 02/2015 - 07/2005
2	Barrett Esophagus (Barrett's Esophagus) 01/2014 - 06/2002

Drug/Important Bio-Agent (IBA)

34	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2002
28	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2021 - 02/2002
14	Messenger RNA (mRNA)IBA 09/2016 - 02/2002
10	Biomarkers (Surrogate Marker)IBA 02/2024 - 03/2008
8	Calcibiotic Root Canal SealerIBA 02/2024 - 04/2008
6	Formaldehyde (Formol)FDA Link 03/2023 - 03/2005
6	EnzymesIBA 10/2016 - 05/2005
6	ELAV-Like Protein 1IBA 09/2016 - 11/2003
6	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 05/2005 - 02/2002
5	ParaffinIBA 03/2023 - 03/2005
5	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2019 - 01/2015
5	Cadherins (E-Cadherin)IBA 06/2015 - 04/2006
5	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2012 - 02/2002
4	Polysaccharides (Glycans)IBA 07/2023 - 11/2018
4	RNA (Ribonucleic Acid)IBA 11/2021 - 02/2015
4	Transforming Growth Factor beta (TGF-beta)IBA 01/2021 - 08/2003
4	DNA (Deoxyribonucleic Acid)IBA 03/2015 - 07/2003
4	Progesterone Receptors (Progesterone Receptor)IBA 09/2011 - 07/2005
3	Blood Proteins (Serum Proteins)IBA 01/2020 - 12/2019
3	Carrier Proteins (Binding Protein)IBA 09/2016 - 01/2008
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2016 - 06/2010
3	CytokinesIBA 01/2016 - 07/2009
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 01/2010
3	Trefoil Factor-1IBA 09/2012 - 06/2003
3	MicroRNAs (MicroRNA)IBA 09/2012 - 04/2010
3	Celecoxib (Celebrex)FDA Link 09/2012 - 06/2003
3	Estrogen ReceptorsIBA 09/2011 - 08/2003
3	Hormones (Hormone)IBA 07/2005 - 02/2002
2	AntigensIBA 11/2023 - 01/2009
2	CateninsIBA 01/2022 - 06/2015
2	LigandsIBA 01/2021 - 01/2016
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2020 - 09/2010
2	MucinsIBA 11/2018 - 01/2017
2	Transcription Factors (Transcription Factor)IBA 10/2018 - 04/2006
2	C-Reactive ProteinIBA 03/2018 - 01/2018
2	AntibodiesIBA 01/2017 - 09/2016
2	Sunitinib (Sutent)FDA Link 01/2017 - 01/2016
2	Tumor Biomarkers (Tumor Markers)IBA 01/2016 - 01/2010
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 01/2010
2	Monoclonal AntibodiesIBA 02/2015 - 06/2002
2	ErbB Receptors (EGF Receptor)IBA 04/2014 - 09/2011
2	Interleukin-1beta (Interleukin 1 beta)IBA 07/2009 - 11/2003
2	Vascular Endothelial Growth Factor CIBA 06/2006 - 03/2005
2	Small Interfering RNA (siRNA)IBA 10/2005 - 11/2003
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2004 - 02/2002
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 06/2002 - 02/2002
2	Protein Isoforms (Isoforms)IBA 06/2002 - 02/2002
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 02/2024
1	stage-specific embryonic antigen-4IBA 11/2023
1	GlycosphingolipidsIBA 11/2023
1	Chimeric Antigen ReceptorsIBA 11/2023
1	Mannose (D-Mannose)IBA 07/2023

Therapy/Procedure

24	Therapeutics 04/2022 - 08/2008
7	Neoadjuvant Therapy 05/2024 - 10/2020
5	Gastrectomy 05/2024 - 01/2023
4	Immunotherapy 11/2023 - 11/2014
4	Drug Therapy (Chemotherapy) 01/2022 - 05/2015
3	Metastasectomy 02/2024 - 01/2022
3	Esophagectomy 01/2023 - 01/2023
2	Lymph Node Excision (Lymph Node Dissection) 01/2023 - 12/2022
2	Fecal Microbiota Transplantation 10/2021 - 01/2021
2	Ligation 01/2021 - 01/2019
2	Palliative Care (Palliative Therapy) 10/2020 - 01/2016
2	Radiotherapy 01/2020 - 01/2016
2	Aftercare (After-Treatment) 01/2016 - 02/2015
2	Chemoprevention 03/2008 - 07/2005
1	Minimally Invasive Surgical Procedures 03/2024